Chronic pain can be caused by many different factors. Often conditions that accompany normal aging may affect bones and joints in ways that cause chronic pain. Other common causes are nerve damage and injuries that fail to heal properly.

 The following conditions have chronic pain as part of their list of symptoms: lupus, mixed connective tissue disease, sarcoidosis, Sjogren's syndrome, thyroid conditions such as Graves' disease and Hashimoto's thyroiditis, Addison's disease, chronic fatigue immune dysfunction syndrome, fibromyalgia, scleroderma, ulcerative colitis, Crohn's disease, celiac disease, rheumatoid arthritis, and multiple sclerosis.

Some kinds of chronic pain have numerous causes.

Disease can also be the underlying cause of chronic pain. Rheumatoid arthritis and osteoarthritis are well-known culprits, but persistent pain may also be due to such ailments as cancer, multiple sclerosis, stomach ulcers, AIDS, and gallbladder disease.

In many cases, however, the source of chronic pain can be a very complex and even mysterious issue to untangle. Although it may begin with an injury or illness, ongoing pain can develop a psychological dimension after the physical problem has healed.

Chronic pain sometimes develops for no apparent reason

Chronic pain may develop for no apparent reason. Despite thorough exams and tests, your doctor may be unable to find a specific physical cause. But this doesn't mean your pain isn't real. the cause of chronic pain isn't found. Years of research have failed to uncover the precise physical causes of many painful ailments, including fibromyalgia and irritable bowel syndrome.