NINDS Myotonia Information Page : Muscle Relaxers

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Last Updated: Oct 6, 2009 - 12:07:30 PM

NINDS Myotonia Information Page
By nih.gov
Jul 23, 2006 - 1:35:00 PM

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Table of Contents (click to jump to sections)
What is Myotonia?
Is there any treatment?
What is the prognosis?
What research is being done?

Organizations
Related NINDS Publications and Information
Additional resources from MEDLINEplus

What is Myotonia?
Myotonia is a neuromuscular disorder characterized by the slow relaxation of the muscles after voluntary contraction or electrical stimulation. Generally, repeated effort is needed to relax the muscles, and the condition improves after the muscles have warmed-up. Individuals with the disorder may have trouble releasing their grip on objects or may have difficulty rising from a sitting position and a stiff, awkward gait. The disorder can affect all muscle groups. It may be acquired or inherited, and is caused by an abnormality in the muscle membrane. Myotonia is a symptom commonly seen in patients with myotonic muscular dystrophy and in a group of disorders called channelopathies (hereditary diseases that are caused by mutations in the chloride sodium or potassium channels that affect the muscle membrane). Myotonia also may be triggered by exposure to cold.

Is there any treatment?

Treatment for myotonia may include quinine, phenytoin, mexiletine, and other anticonvulsant drugs. Physical therapy and other rehabilitative measures may help muscle function.

What is the prognosis?

Myotonia can be a static or a progressive disorder. Symptoms may improve later in life.

What research is being done?

The NINDS supports and conducts an extensive research program on neuromuscular disorders such as myotonia. The goals of this research are to learn more about these disorders, and to find ways to treat, prevent, and cure them.

Select this link to view a list of studies currently seeking patients.

Organizations

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institutes of Health, DHHS
31 Center Dr., Rm. 4C02 MSC 2350
Bethesda, MD 20892-2350
NIAMSinfo@mail.nih.gov
http://www.niams.nih.gov
Tel: 301-496-8190 877-22-NIAMS (226-4267)

Muscular Dystrophy Association
3300 East Sunrise Drive
Tucson, AZ 85718-3208
mda@mdausa.org
http://www.mda.org
Tel: 520-529-2000 800-344-4863
Fax: 520-529-5300

Related NINDS Publications and Information

NINDS Myotonia Congenita Information Page
Myotonia congenita information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS).

Prepared by:
Office of Communications and Public Liaison
National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, MD 20892

NINDS health-related material is provided for information purposes only and does not necessarily represent endorsement by or an official position of the National Institute of Neurological Disorders and Stroke or any other Federal agency. Advice on the treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient's medical history.

All NINDS-prepared information is in the public domain and may be freely copied. Credit to the NINDS or the NIH is appreciated.

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Last updated February 17, 2006

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