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General Health : HIV AIDS Last Updated: Oct 6, 2009 - 12:07:30 PM



AIDS Drugs Have Saved 3 Million Years of Life in the United States
Increasingly effective HIV therapy ¡ª including a decade of highly active antiretroviral therapy (HAART) ¡ª has provided 3 million years of extended life to Americans with AIDS since 1989, report researchers funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH).

Alcohol and HIV/AIDS
People with alcohol use disorders are more likely than the general population to contract HIV (human immunodeficiency virus).1 Similarly, people with HIV are more likely to abuse alcohol at some time during their lives (1).

Analysis Shows Infants of Mothers Infected With HIV Face Nearly Constant Risk For HIV Infection For Duration of Breastfeeding
After four weeks of age, infants who breast feed from mothers infected with HIV continue to be at risk for infection with HIV for as long as they breastfeed, according to an analysis conducted and funded by the National Institute of Child Health and Human Development of the National Institutes of Health. Previously, researchers thought the risk for being infected with the virus from breast milk diminished as an infant grew older.

Depression and HIV/AIDS
Research has enabled many men and women, and young people living with human immunodeficiency virus (HIV), the virus that causes acquired immunodeficiency syndrome (AIDS), to lead fuller, more productive lives. As with other serious illnesses such as cancer, heart disease or stroke, however, HIV often can be accompanied by depression, an illness that can affect mind, mood, body, and behavior. Treatment for depression helps people manage both diseases, thus enhancing survival and quality of life.

HIV Infection and AIDS: An Overview
AIDS (acquired immunodeficiency syndrome) was first reported in the United States in 1981 and has since become a major worldwide epidemic. AIDS is caused by HIV (human immunodeficiency virus). By killing or damaging cells of the body's immune system, HIV progressively destroys the body's ability to fight infections and certain cancers. People diagnosed with AIDS may get life-threatening diseases called opportunistic infections, which are caused by microbes such as viruses or bacteria that usually do not make healthy people sick.

HIV Infection in Adolescents and Young Adults in the U.S.
There is a rising concern about the effects of HIV/AIDS among adolescents and young adults between ages of 13 to 24 in the United States. The Centers for Disease Control and Prevention (CDC) reported 40,049 cumulative cases of AIDS among people ages 13 to 24 through 2004. Since the epidemic began, an estimated 10,129 adolescents and young adults with AIDS have died and the proportion diagnosed with AIDS has also increased. Likewise, the proportion of adolescents and young adults with an AIDS diagnosis has increased from 3.9 percent in 1999 to 4.2 percent in 2004.

HIV Infection in Infants and Children
The National Institute of Allergy and Infectious Diseases (NIAID) has a lead role in research devoted to children infected with HIV (human immunodeficiency virus), the virus that causes AIDS (acquired immunodeficiency syndrome). NIAID-supported researchers are developing and refining treatments to prolong the survival and improve the quality of life of HIV-infected infants and children through the Pediatric AIDS Clinical Trials Group (PACTG).

HIV Infection in Women
The number of women with HIV (human immunodeficiency virus) infection and AIDS (acquired immunodeficiency syndrome) has increased steadily worldwide. By the end of 2005, according to the World Health Organization (WHO), 17.5 million women worldwide were infected with HIV.

HIV and AIDS
HIV stands for human immunodeficiency (say: ih-myoo-no-dih-fih-shun-see) virus. AIDS stands for acquired immunodeficiency syndrome. HIV is actually the virus that causes the disease AIDS.

HIV/AIDS and the Flu
HIV (human immunodeficiency virus) is the virus that causes AIDS (Acquired Immune Deficiency Syndrome). HIV kills or damages cells in the body’s immune system, gradually destroying the body’s ability to fight infection and certain cancers. An estimated 850,000 to 950,000 people are infected with HIV in the United States.

How HIV Causes AIDS
A significant component of the research effort of the National Institute of Allergy and Infectious Diseases (NIAID) is devoted to the pathogenesis of HIV (human immunodeficiency virus) disease. Studies on pathogenesis address the complex mechanisms that result in the destruction of the immune system of an HIV-infected person. A detailed understanding of HIV and how it establishes infection and causes AIDS (acquired immunodeficiency syndrome) is crucial to identifying and developing effective drugs and vaccines to fight HIV and AIDS. This fact sheet summarizes the state of knowledge in this area.

How do I protect other people from my HIV?
The surest way to avoid transmission of sexually transmitted diseases is to abstain from sexual intercourse, or to be in a long-term mutually monogamous relationship with a partner who has been tested and you know is uninfected.


International Trial of Two Microbicides Begins
A large, multisite trial designed to examine the safety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, represents a partnership among various research institutions in Africa and the United States.

LIVING WITH HIV/AIDS
HIV is the virus that causes AIDS. The first cases of AIDS were identified in the United States in 1981, but the virus probably existed here and in other parts of the world for many years before that. In 1984, scientists proved that HIV causes AIDS.

NIDA InfoFacts: Drug Abuse and AIDS
Behavior associated with drug abuse is now the single largest factor in the spread of HIV infection in the United States. HIV is the Human Immunodeficiency Virus, which causes Acquired Immunodeficiency Syndrome, or AIDS. AIDS is a condition characterized by a defect in the body's natural immunity to diseases, and individuals who suffer from it are at risk for severe illnesses that are usually not a threat to anyone whose immune system is working properly. Although many individuals who have AIDS or carry HIV may live for many years with treatment, there is no known cure or vaccine.

NINDS Neurological Complications of AIDS Information Page
AIDS is primarily an immune system disorder caused by the human immunodeficiency virus (HIV), but it can also affect the nervous system. HIV does not appear to directly invade nerve cells but it jeopardizes their health and function, causing symptoms such as confusion, forgetfulness, behavioral changes, severe headaches, progressive weakness, loss of sensation in the arms and legs, stroke, cognitive motor impairment, or damage to the peripheral nerves.

National Institutes of Health on The 25th Anniversary of the First Published Reports of AIDS
Monday, June 5, 2006, marks the 25th anniversary of the first reported cases of what is now known as the acquired immunodeficiency syndrome (AIDS). From a handful of initial reports in the Morbidity and Mortality Weekly Report, AIDS has grown into a global pandemic affecting men, women and children in nearly every country in the world.

Neurological Complications of AIDS Fact Sheet
AIDS (acquired immune deficiency syndrome) is a condition that occurs in the most advanced stages of human immunodeficiency virus (HIV) infection. It may take many years for AIDS to develop following the initial HIV infection.

Preventing Infections During Travel
In the United States or abroad? For business or pleasure? When you travel, you risk coming into contact with germs you might not find at home. Many of these germs can make you very sick.

Preventing Infections During Travel
In the United States or abroad? For business or pleasure? When you travel, you risk coming into contact with germs you might not find at home. Many of these germs can make you very sick.

Preventing Infections from Pets
Animals can have cryptosporidiosis ("crypto"), toxoplasmosis ("toxo"), Mycobacterium avium complex ("MAC"), and other diseases. These diseases can give you problems like severe diarrhea, brain infections, and skin lesions. You can learn more about many of these diseases and how to prevent them from other brochures in this series. These are listed at the end of this brochure.

Scientists Discover Enzyme Crucial to HIV Replication
Scientists have discovered that a cellular enzyme helps ferry HIV genetic instructions out of the cell nucleus where they can then be translated into proteins to begin their most destructive work. The cellular enzyme represents a potential new target for developing improved HIV drugs, say the researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and the McGill University AIDS Center.

Scientists Discover Key Genetic Factor in Determining HIV/AIDS Risk
People with more copies of a gene that helps to fight HIV are less likely to become infected with the virus or to develop AIDS than those of the same geographical ancestry, such as European Americans, who have fewer copies of the gene, according to a study funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). The findings help to explain why some people are more prone to HIV/AIDS than others.

Scientists Discover New Approaches to Manipulating AIDS Virus
Researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, have discovered new information about how human immunodeficiency virus (HIV), the virus that causes acquired immune deficiency (AIDS), possibly evades eradication from the body. In a study published in the August 16, 2004 Journal of Virology*, NCI HIV and AIDS Malignancy Branch scientists identified several possible gene targets and two drugs to flush out long-lasting HIV reservoirs that current treatments do not affect. They also established a connection between HIV and several other genes not previously associated with
the virus and found new possible targets for blocking HIV replication.


Sexually Transmitted Diseases (STDs) and HIV/AIDS in Men
A sexually transmitted disease, or STD, is an infection or disease passed from person to person through sexual contact. You can get and pass STDs through vaginal, anal, or oral sex. The United States has the highest rates of STDs in the industrialized world. In the United States alone, an estimated 15.3 million new cases of STDs are reported each year. The scary thing about STDs for men is that not all men get symptoms, even if they are infected.

Testing HIV Positive ¨C Do I Have AIDS?
A positive HIV test result means that you are infected with HIV (Human Immunodeficiency Virus), the virus that causes AIDS (Acquired Immune Deficiency Syndrome). Being infected with HIV does not mean that you have AIDS right now. However, if left untreated, HIV infection damages a person¡¯s immune system and can progress to AIDS.

The HIV-AIDS Connection
The acquired immunodeficiency syndrome (AIDS) was first recognized in 1981 and has since become a major worldwide pandemic. Abundant evidence indicates that AIDS is caused by the human immunodeficiency virus (HIV) , which was discovered in 1983. By leading to the destruction and/or functional impairment of cells of the immune system, notably CD4+ T cells, HIV progressively destroys the body's ability to fight infections and certain cancers.

Tuberculosis: The Connection between TB and HIV (the AIDS virus)
People infected with HIV (the virus that causes AIDS) are more likely than uninfected people to get sick with other infections and diseases. Tuberculosis (TB) is one of these diseases.

What can I expect when I go to the doctor?
At your first appointment your doctor will ask you questions, do a checkup, draw blood, and do a tuberculosis skin test and other tests. Your doctor also may give you some immunizations (shots). Tell your doctor about any health problems you are having so that you can get treatment. You also should ask your doctor any questions you have about HIV or AIDS, such as what to do if your medicine makes you sick, where to get help in quitting smoking or drug use, or how to eat healthy foods.

When your doctor draws blood, it is used for many tests, including the CD4 cell count and "viral load testing." Viral load testing measures the amount of HIV in your blood. Viral load tests help predict what will happen next with your HIV infection if you don¡¯t get treatment. They are used with CD4 cell counts to decide when to start and when to change your drug therapies.

Keep your follow-up appointments with your doctor. At follow-up appointments you and your doctor will talk about your test results, and he or she may prescribe medicine for you.


What is HIV and how did I get it?
The first cases of AIDS were identified in the United States in 1981, but it most likely existed here and in other parts of the world for many years before that. In 1984 scientists proved that HIV causes AIDS.

What is the difference between HIV and AIDS?
When HIV enters your body, it infects your "CD4 cells" and kills them. CD4 cells sometimes called T-helper cells) help your body fight off infection and disease. Usually, CD4 cell counts in someone with a healthy immune system range from 500 to 1800.

When you lose CD4 cells, your immune system breaks down and you can¡¯t fight infections and diseases as well. When your CD4 cell count goes under 200, doctors say you have AIDS. Doctors also say you have AIDS if you have HIV and certain diseases, such as tuberculosis or Pneumocystis carinii [NEW-mo-SIS-tis CA-RIN-nee-eye] pneumonia (PCP), even if your CD4 cell count is over 200.


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